characters talk to the camera, but in context they're talking to another character (who is holding the camera) rather than the audience. no characters express awareness that they are fictional
Nobody is physically tortured, (SPOILER) but an elderly character is forced to relieve emotional and traumatic moments while unknowingly participating in an experiment
SPOILER: No characters cheat, but it's implied in one scene that a man is having an affair, but then cuts away. It's later revealed that she's a home nurse, and he was not having an affair.