Check man in a dress trigger for more details but I would say, yes.
The "man in a dress" joke in s1 ep2 really further perpetuates the hateful stereo type that trans women are just feminine men who are looking to perv on women (benny dresses up as a cheerleader to perv on the girls and later tries to join them in the shower, then tries to join them at a sleepover)
Sarah V*s ectoplasm on Benny, Rory, and Ethan in S1 E12. It appears like green transparent slime and isn’t very triggering at all.
In season 1 episode 13, Ethan is saved by Sarah and resting. at the very end Rory mentions him and Ethan v*ing in the past briefly before Erica hits him on the shoulder to stop him from talking about it anymore.
In episode 12 of season 2, Rory grabs onto the lucifractor and it effects him negatively. He appears to hold onto his stomach and be wobbly, almost as if he’s going to v* but he never does.
S1E2 - Benny and Ethan dress as cheerleaders to infiltrate the cheerleading team and stop a witch. They’re also seen attempting to get into the women’s locker room, which can be triggering as a transmisogynistic stereotype.