Not exactly outed. A chatacter’s father finds out his son is gay after seeing the latter holding a man’s hand. The father then spews hate speech at his son until the latter commits suicide
Side character is told to lose weight by her boss. Many women discuss being unhappy in their bodies and using fad diets to lose weight. Main character combats this very logically and promotes a healthy relationship with food.
To me, both Elizabeth and Calvin seem autistic-coded, but this is not explicitly said. A lot of people react negatively to Elizabeth for sexist reasons but also because she speaks rather bluntly. I wouldn’t say it qualifies as abuse though